Carl Langhein was born in Hamburg, the son of Carl, a wallpaperer and decorator, and his wife Louise Langhein. He attended elementary school and then completed an apprenticeship as a lithographer. At the same time, he took drawing classes at the trade school in Hamburg. After completing his apprenticeship, he worked as a lithographer at the Kunstanstalt Kaufbeuren in the Allgäu region. He then continued his studies at the Royal Academy of Arts in Berlin and the Academy of Fine Arts in Karlsruhe. In 1900, he became a lecturer at the School of Applied Arts in Karlsruhe. Langhein had already moved to Otterndorf, where he built a studio house and married Anna Elisabeth Schmider in 1898. During the First World War, Langhein served in the Imperial Navy. In 1918, he founded the Hanseatischer Kunstverlag publishing house, based in Hamburg. Shortly afterwards, Langhein fell ill and was admitted to the Lüneburg institution in 1927. He was murdered on 16 June 1941 in the Hadamar killing centre. Langhein was a successful artist and had important students, such as Georg Scholz, Georg Tappert and Wilhelm Laage. His works are represented in various collections, and streets and roads have been named after him.